By Public Transportation - total trip time of 2 hours each way ($3.50 per person)
Catch the 760 Metro Bus towards Lynwood at 4th/Beaudry (2 blocks from Jerry's Motel)
Get off at 7th & Flower and transfer to the 460 Metro Bus towards Disneyland
By City Taxi - total trip time of 45 minutes
A taxi will cost approximately $100 each way including tip.
By Chartered Tour Bus - total trip time of 1 hour
Lux Bus America has a pickup location at the Westin Bonaventure Hotel which is located 4 blocks from Jerry's Motel. As of October 2014, a roundtrip tickets costs $45 per person. You can also purchase Disneyland tickets directly through them.
See links below for details:
Starline Tours also offers similar packages